In 1937 Anguiano joined the Revolutionary Writers and Artists League. Together, with Alfredo Zalce and Pablo O'Higgins, he was also a founding member of thePopular Graphics Workshop, where artist practised a graphic style based on Mexico's folk traditions. This was due to the powerful influence of the recently discovered Jose Guadalupe Posada and Goya.

Raúl Anguiano belongs to the so-called "Third Generation" of post-revolutionary painters, along with Juan O'Gorman, Jorge González Camarena, José Chávez Morado, Alfredo Zalce, Jesús Guerrero Galván and Julio Castellanos, all known for being unorthodox, associated in politics and in art, while at the same time, holding to certain traditional canons. Anguiano's work is viewed as an expression of its time because of its undeniably Mexican flavour, and the link to his people is clear, not only in his murals but also on canvas, etchings, pencil and ink drawings, lithographs and illustrations, and also more recently in sculpture and ceramics. Without compromising his personality or ethnic roots, and at the same time not allowing them to limit him, Anguiano has vindicated and taken advantage of the principles of modern art, giving him a universal and transcending character of his boundary work.

Anguiano held his first solo exhibition, entitled "Raúl Anguiano and Máximo Pacheco" at the Palace of Fine Arts in Mexico City, in 1935; and in 1940 he took part in his first collective exhibition "Twenty Centuries of Mexican Art". These were followed by more than 100 shows in many countries as Cuba, Chile, Colombia, Brazil, United States, France, Italy, the former Soviet Union, Israel, Germany and Japan. His most recent exhibitions include the presentation of a series of four colour lithographs, held at the Hall of Graphic Arts SAGA 88, from 1989 to 1990, in Paris; and the retrospective look at Anguiano's work in graphics (1938-1940), held at the National Print Museum in Mexico City in 1990.

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